Pill Bottles Containing MedicationMany medications, both over the counter and prescription can cause neurotransmitter depletion over time. This usually happens because the drug/medication forces the body to release more neurotransmitter and/or blocks the reuptake of neurotransmitter into the neurons where they are protected. This increases the degradation of neurotransmitters and exacerbates neurotransmitter imbalances over time. This is what is happening when a drug (or class of drugs such as SSRIs) stops working – the levels of stored neurotransmitters have dropped so low due to the medication that there is no longer enough neurotransmitter for the drugs to push around.

Other medications can cause permanent damage to the neurotransmitter receptors or the neurons themselves. This damage is irreversible and called ‘neurotoxicity’. Even though neurotoxicity is irreversible, it can be managed with the proper use of amino acid therapy.

Here is a partial list of drugs and medications that can deplete neurotransmitter levels:

TABLE – 3 COLUMNS

Anti-Depressants (SSRIs) including: Luvox, Zoloft, Prozac, Celexa, Paxil

Trazadone (Deseryl)

Sinequan (Doxepin)

Serzone

Effexor

Meridia

Phendimetrazin (Bontril)

Phentermine (Adipex)

Phenylpropanolamine (Dexedrine)

Tenuate

Mazindol

Fenfluramine

Amphetamines (including Ritalin)

Ephedra

Caffeine

Alcohol

Nicotine

Imitrex

Zomig

Maxalt

Amerge

Amitriptyline (Elavil)

Nortryptyline (Norpramin)

Remeron

Wellbutrin (Zyban)

Thioridazine (Mylan)

Barbiturates

Marijuana/THC

Cocaine

Heroin

Opioids